Operation not permitted "NSPOSIXERRORDOMAIN 1" on Safari

It started happen all of sudden that you are not able to access very specific things on intranet and internet on safari but things work normally on other browsers like Chrome and Firefox.

Solution:

Just check if you are able access them in Safari Private Window.

If yes, then your mac has something installed which is preventing safari to communicate with intranet and internet things.

Run this command in terminal and check its output.

kextstat -kl | awk ' !/apple/ { print $6 } '

My output was:

So, i tried to uninstall the things which were very less critical. Like uninstalled Virtual box and it fixed the issue. In your case, there could be some other thing which could fix it after uninstalling it.